Coupled protein quality control during nonsense-mediated mRNA decay

Translation of mRNAs containing premature termination codons (PTCs) results in truncated protein products with deleterious effects. Nonsense-mediated decay (NMD) is a surveillance pathway responsible for detecting PTC containing transcripts. Although the molecular mechanisms governing mRNA degradati...

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Detalles Bibliográficos
Autores principales: Inglis, Alison J., Guna, Alina, Gálvez-Merchán, Ángel, Pal, Akshaye, Esantsi, Theodore K., Keys, Heather R., Frenkel, Evgeni M., Oania, Robert, Weissman, Jonathan S., Voorhees, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234110/
https://www.ncbi.nlm.nih.gov/pubmed/37218462
http://dx.doi.org/10.1242/jcs.261216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234110/
https://www.ncbi.nlm.nih.gov/pubmed/37218462
http://dx.doi.org/10.1242/jcs.261216

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