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Hypothalamic PVN CRH Neurons Signal Through PVN GABA Neurons to Suppress GnRH Pulse Generator Frequency in Female Mice

Corticotropin-releasing hormone (CRH) neurons in the paraventricular nucleus of the hypothalamus (PVN) are central to the stress response. Chemogenetic activation of PVN CRH neurons decreases LH pulse frequency but the mechanism is unknown. In the present study, optogenetic stimulation of PVN CRH ne...

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Detalles Bibliográficos
Autores principales: McIntyre, Caitlin, Li, Xiao Feng, Ivanova, Deyana, Wang, Jun, O’Byrne, Kevin T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234117/
https://www.ncbi.nlm.nih.gov/pubmed/37246581
http://dx.doi.org/10.1210/endocr/bqad075