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GABA treatment does not induce neogenesis of new endocrine cells from pancreatic ductal cells

Previous studies indicated that ductal cells can contribute to endocrine neogenesis in adult rodents after alpha cells convert into beta cells. This can occur through Pax4 mis-expression in alpha cells or through long-term administration of gamma-aminobutyric acid (GABA) to healthy mice. GABA has al...

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Detalles Bibliográficos
Autores principales: Wang, Shihao, Dong, Xin, Maazi, Mahan, Chen, Nan, Mahil, Amar, Kopp, Janel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234131/
https://www.ncbi.nlm.nih.gov/pubmed/37258189
http://dx.doi.org/10.1080/19382014.2023.2219477