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Pharmacogenetics of tenofovir renal toxicity in HIV-positive Southern Africans

Renal toxicity is more common with tenofovir disoproxil fumarate (TDF) than with tenofovir alafenamide fumarate (TAF). We investigated whether polymorphisms in genes relevant to tenofovir disposition affect renal toxicity among HIV-positive Southern Africans. METHODS: Genetic sub-study of adults ran...

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Detalles Bibliográficos
Autores principales: Mateza, Somila, Bradford, Yuki, Maartens, Gary, Sokhela, Simiso, Chandiwana, Nomathemba C., Venter, Willem D.F., Post, Frank A., Ritchie, Marylyn D., Haas, David W., Sinxadi, Phumla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234323/
https://www.ncbi.nlm.nih.gov/pubmed/37099271
http://dx.doi.org/10.1097/FPC.0000000000000491