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Antiviral activities of two nucleos(t)ide analogs against vaccinia, mpox, and cowpox viruses in primary human fibroblasts

Many poxviruses are significant human and animal pathogens, including viruses that cause smallpox and mpox (formerly monkeypox). Identifying novel and potent antiviral compounds is critical to successful drug development targeting poxviruses. Here we tested two compounds, nucleoside trifluridine, an...

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Detalles Bibliográficos
Autores principales: Dsouza, Lara, Pant, Anil, Offei, Samuel, Priyamvada, Lalita, Pope, Blake, Satheshkumar, Panayampalli S., Wang, Zhengqiang, Yang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234405/
https://www.ncbi.nlm.nih.gov/pubmed/37270160
http://dx.doi.org/10.1016/j.antiviral.2023.105651