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Shadow enhancers mediate trade-offs between transcriptional noise and fidelity

Enhancers are stretches of regulatory DNA that bind transcription factors (TFs) and regulate the expression of a target gene. Shadow enhancers are two or more enhancers that regulate the same target gene in space and time and are associated with most animal developmental genes. These multi-enhancer...

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Detalles Bibliográficos
Autores principales: Fletcher, Alvaro, Wunderlich, Zeba, Enciso, German
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234526/
https://www.ncbi.nlm.nih.gov/pubmed/37205714
http://dx.doi.org/10.1371/journal.pcbi.1011071