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Modelling the structures of frameshift-stimulatory pseudoknots from representative bat coronaviruses
Coronaviruses (CoVs) use −1 programmed ribosomal frameshifting stimulated by RNA pseudoknots in the viral genome to control expression of enzymes essential for replication, making CoV pseudoknots a promising target for anti-coronaviral drugs. Bats represent one of the largest reservoirs of CoVs and...
Autores principales: | Sekar, Rohith Vedhthaanth, Oliva, Patricia J., Woodside, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234561/ https://www.ncbi.nlm.nih.gov/pubmed/37205708 http://dx.doi.org/10.1371/journal.pcbi.1011124 |
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