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Bone Marrow-Derived Mesenchymal Stem Cells and γ-Secretase Inhibitor Treatments Suppress Amyloid-β25–35-Induced Cognitive Impairment in Rat Dams and Cortical Degeneration in Offspring

Alzheimer's disease (AD) is the most frequent cause of age-related neurodegeneration and ensuing cognitive impairment. Progressive deposition of extracellular amyloid beta (Aβ) aggregates (plaques) and intracellular hyperphosphorylated Tau protein (p-Tau) are the core pathological markers of AD...

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Detalles Bibliográficos
Autores principales: Gaber, Asmaa, Elbakry, Ahlam M., Aljarari, Rabab M., Jaber, Fatima A., Khadrawy, Yasser A., Sabry, Dina, Abo-ELeneen, Rasha E., Ahmed, Osama M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234728/
https://www.ncbi.nlm.nih.gov/pubmed/37274020
http://dx.doi.org/10.1155/2023/2690949