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Wee1 epigenetically modulates H2B mono‐ubiquitination at K120 lysine and DNA double‐strand break repair through phosphorylation of H2BY37‐dependent manner in small‐cell lung cancer

BACKGROUND: DNA damage repair is a crucial mechanism highly related to therapy resistance for various therapeutic strategies. Our previous results have shown that the degree of drug resistance in small‐cell lung cancer (SCLC) cell lines was proportional to both the transcription and expression level...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoliang, Wen, Xiaohua, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234777/
https://www.ncbi.nlm.nih.gov/pubmed/37102239
http://dx.doi.org/10.1111/1759-7714.14862