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Tumor‐derived exosomal miR‐148b‐3p mediates M2 macrophage polarization via TSC2/mTORC1 to promote breast cancer migration and invasion

BACKGROUND: Emerging evidence has revealed that tumor‐associated macrophages (TAMs) and exosomes play a crucial role in the microenvironment for tumor growth. However, the mechanisms through which exosomal miRNAs modulate TAMs and tumor development in breast cancer are not fully understood. METHODS:...

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Detalles Bibliográficos
Autores principales: Hao, Chong, Sheng, Zhimei, Wang, Wenhao, Feng, Ruijun, Zheng, Yuanhang, Xiao, Qinpei, Zhang, Baogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234784/
https://www.ncbi.nlm.nih.gov/pubmed/37144254
http://dx.doi.org/10.1111/1759-7714.14891