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The transmembrane domain of Frey1 harbors a transplantable inhibitory motif for intramembrane proteases

Although aspartic intramembrane-cleaving proteases (I-CLIPs) are crucial switches of multiple signaling pathways and involved in several devastating diseases, little is known about their physiological regulation. We have recently identified Frey regulator of sperm-oocyte fusion 1 (Frey1) as an inhib...

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Detalles Bibliográficos
Autores principales: Contreras, Whendy, Bazan, J. Fernando, Mentrup, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234869/
https://www.ncbi.nlm.nih.gov/pubmed/37261541
http://dx.doi.org/10.1007/s00018-023-04823-7