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The transmembrane domain of Frey1 harbors a transplantable inhibitory motif for intramembrane proteases
Although aspartic intramembrane-cleaving proteases (I-CLIPs) are crucial switches of multiple signaling pathways and involved in several devastating diseases, little is known about their physiological regulation. We have recently identified Frey regulator of sperm-oocyte fusion 1 (Frey1) as an inhib...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234869/ https://www.ncbi.nlm.nih.gov/pubmed/37261541 http://dx.doi.org/10.1007/s00018-023-04823-7 |