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Protocol development to further differentiate and transition stem cell-derived pancreatic progenitors from a monolayer into endocrine cells in suspension culture

The generation of functional β-cells from human pluripotent stem cells (hPSCs) for cell replacement therapy and disease modeling of diabetes is being investigated by many groups. We have developed a protocol to harvest and aggregate hPSC-derived pancreatic progenitors generated using a commercially...

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Detalles Bibliográficos
Autores principales: Braam, Mitchell J. S., Zhao, Jia, Liang, Shenghui, Ida, Shogo, Kloostra, Nick K., Iworima, Diepiriye G., Tang, Mei, Baker, Robert K., Quiskamp, Nina, Piret, James M., Kieffer, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235054/
https://www.ncbi.nlm.nih.gov/pubmed/37264038
http://dx.doi.org/10.1038/s41598-023-35716-1