Cargando…

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Kinetochores assemble on centromeres via histone H3 variant CENP-A and low levels of centromere transcripts (cenRNAs). The latter are ensured by the downregulation of RNA polymerase II (RNAPII) activity, and cenRNA turnover by the nuclear exosome. Using S. cerevisiae, we now add protein kinase Rio1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smurova, Ksenia, Damizia, Michela, Irene, Carmela, Stancari, Stefania, Berto, Giovanna, Perticari, Giulia, Iacovella, Maria Giuseppina, D’Ambrosio, Ilaria, Giubettini, Maria, Philippe, Réginald, Baggio, Chiara, Callegaro, Elisabetta, Casagranda, Andrea, Corsini, Alessandro, Polese, Vincenzo Gentile, Ricci, Anna, Dassi, Erik, De Wulf, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235086/ https://www.ncbi.nlm.nih.gov/pubmed/37263996 http://dx.doi.org/10.1038/s41467-023-38920-9

Ejemplares similares

Centromere and Pericentromere Transcription: Roles and Regulation … in Sickness and in Health
por: Smurova, Ksenia, et al.
Publicado: (2018)

Aurora B SUMOylation Is Restricted to Centromeres in Early Mitosis and Requires RANBP2
por: Di Cesare, Erica, et al.
Publicado: (2023)

The Centromere: Chromatin Foundation for the Kinetochore Machinery
por: Fukagawa, Tatsuo, et al.
Publicado: (2014)

The RioK1 network determines p53 activity at multiple levels
por: Damizia, Michela, et al.
Publicado: (2023)

The Mitotic Apparatus and Kinetochores in Microcephaly and Neurodevelopmental Diseases
por: Degrassi, Francesca, et al.
Publicado: (2019)

Conservation of the Centromere/Kinetochore Protein ZW10
por: Starr, Daniel A., et al.
Publicado: (1997)

The four causes: the functional architecture of centromeres and kinetochores
por: McAinsh, Andrew D., et al.
Publicado: (2022)

Bridgin connects the outer kinetochore to centromeric chromatin
por: Sridhar, Shreyas, et al.
Publicado: (2021)

Simple centromere, complex kinetochore: linking spindle microtubules and centromeric DNA in budding yeast
por: Cheeseman, Iain M., et al.
Publicado: (2002)

Anti-centromere antibodies target centromere–kinetochore macrocomplex: a comprehensive autoantigen profiling
por: Kajio, Nobuhiko, et al.
Publicado: (2021)

The centromere-kinetochore complex: a repeat subunit model
Publicado: (1991)

Phylogenetic and structural analysis of centromeric DNA and kinetochore proteins
por: Meraldi, Patrick, et al.
Publicado: (2006)

Distribution of kinetochore (centromere) antigen in mammalian cell nuclei
Publicado: (1981)

In vitro centromere and kinetochore assembly on defined chromatin templates
por: Guse, Annika, et al.
Publicado: (2011)

Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA
por: Ólafsson, Guðjón, et al.
Publicado: (2020)

The kinetochore prevents centromere-proximal crossover recombination during meiosis
por: Vincenten, Nadine, et al.
Publicado: (2015)

Inner Kinetochore Protein Interactions with Regional Centromeres of Fission Yeast
por: Thakur, Jitendra, et al.
Publicado: (2015)

Architecture of the CBF3-Centromere Complex of the Budding Yeast Kinetochore
por: Yan, Kaige, et al.
Publicado: (2018)

Plasticity in centromere organization and kinetochore composition: Lessons from diversity
por: Ishii, Midori, et al.
Publicado: (2022)

How the kinetochore couples microtubule force and centromere stretch to move chromosomes
por: Suzuki, Aussie, et al.
Publicado: (2016)

Repetitive centromeric satellite RNA is essential for kinetochore formation and cell division
por: Rošić, Silvana, et al.
Publicado: (2014)

Repetitive centromeric satellite RNA is essential for kinetochore formation and cell division
por: Rošić, Silvana, et al.
Publicado: (2014)

The Coordination of Centromere Replication, Spindle Formation, and Kinetochore–Microtubule Interaction in Budding Yeast
por: Liu, Hong, et al.
Publicado: (2008)

CENP-B: a major human centromere protein located beneath the kinetochore
Publicado: (1990)

Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases
por: Jaqaman, Khuloud, et al.
Publicado: (2010)

The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly
por: Hori, Tetsuya, et al.
Publicado: (2013)

CENP-A: the key player behind centromere identity, propagation, and kinetochore assembly
por: De Rop, Valérie, et al.
Publicado: (2012)

Decoding Polo-like kinase 1 signaling along the kinetochore-centromere axis
por: Lera, Robert F., et al.
Publicado: (2016)

Bub1 targeting to centromeres is sufficient for Sgo1 recruitment in the absence of kinetochores
por: Williams, Samantha J., et al.
Publicado: (2016)

The centromere comes into focus: from CENP-A nucleosomes to kinetochore connections with the spindle
por: Kixmoeller, Kathryn, et al.
Publicado: (2020)

Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome
por: Yan, Kaige, et al.
Publicado: (2019)

Kinetochore individualization in meiosis I is required for centromeric cohesin removal in meiosis II
por: Gryaznova, Yulia, et al.
Publicado: (2021)

Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere
por: Dendooven, Tom, et al.
Publicado: (2023)

Topoisomerase II alpha is associated with the mammalian centromere in a cell cycle- and species-specific manner and is required for proper centromere/kinetochore structure
Publicado: (1996)

Loss of sister kinetochore co-orientation and peri-centromeric cohesin protection after meiosis I depends on cleavage of centromeric REC8
por: Ogushi, Sugako, et al.
Publicado: (2021)

Molecular architecture of the kinetochore-microtubule attachment site is conserved between point and regional centromeres
por: Joglekar, Ajit P., et al.
Publicado: (2008)

Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae
por: Mythreye, Karthikeyan, et al.
Publicado: (2003)

Human Condensin Function Is Essential for Centromeric Chromatin Assembly and Proper Sister Kinetochore Orientation
por: Samoshkin, Alexander, et al.
Publicado: (2009)

Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores
por: Bekier, Michael E., et al.
Publicado: (2015)

Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy
por: Zhang, Weiguo, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_h1clvncttqvjkvfo5j1ajel8d7