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High-pressure studies in the supercooled and glassy state of the strongly associated active pharmaceutical ingredient—ticagrelor
In this paper, the molecular dynamics at different thermodynamic conditions of hydrogen-bonded (H-bonded) active pharmaceutical ingredient—ticagrelor (TICA) have been investigated. Extensive high-pressure (HP) dielectric studies revealed surprising high sensitivity of the structural (α)-relaxation t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235114/ https://www.ncbi.nlm.nih.gov/pubmed/37264074 http://dx.doi.org/10.1038/s41598-023-35772-7 |