Chronic, Mild Hypothermic Environmental Temperature Does Not Ameliorate Cognitive Deficits in an Alzheimer’s Disease Mouse

Metabolic dysfunction increases with age and is a contributing factor to Alzheimer’s disease (AD) development. We have previously observed impaired insulin sensitivity and glucose homeostasis in the APP/PS1 model of AD. To improve these parameters, we chronically exposed male and female mice to mild...

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Detalles Bibliográficos
Autores principales: McFadden, Samuel, Sime, Lindsey N, Cox, MaKayla F, Findley, Caleigh A, Peck, Mackenzie R, Quinn, Kathleen, Fang, Yimin, Bartke, Andrzej, Hascup, Erin R, Hascup, Kevin N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
THE JOURNAL OF GERONTOLOGY: Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235199/
https://www.ncbi.nlm.nih.gov/pubmed/36398842
http://dx.doi.org/10.1093/gerona/glac223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235199/
https://www.ncbi.nlm.nih.gov/pubmed/36398842
http://dx.doi.org/10.1093/gerona/glac223

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