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Expression of the primate-specific LINC00473 RNA in mouse neurons promotes excitability and CREB-regulated transcription

The LINC00473 (Lnc473) gene has previously been shown to be associated with cancer and psychiatric disorders. Its expression is elevated in several types of tumors and decreased in the brains of patients diagnosed with schizophrenia or major depression. In neurons, Lnc473 transcription is strongly r...

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Detalles Bibliográficos
Autores principales: Pruunsild, Priit, Bengtson, C. Peter, Loss, Isabel, Lohrer, Benjamin, Bading, Hilmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235438/
https://www.ncbi.nlm.nih.gov/pubmed/37019214
http://dx.doi.org/10.1016/j.jbc.2023.104671