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A tetravalent nanoparticle vaccine elicits a balanced and potent immune response against dengue viruses without inducing antibody-dependent enhancement

Dengue fever is a global health threat caused by the dengue virus (DENV), a vector-borne and single-stranded RNA virus. Development of a safe and efficacious vaccine against DENV is a demanding challenge. The greatest pitfall in the development of vaccines is antibody-dependent enhancement (ADE), wh...

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Detalles Bibliográficos
Autores principales: Chen, Qier, Li, Rong, Wu, Bolin, Zhang, Xu, Zhang, Hui, Chen, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235449/
https://www.ncbi.nlm.nih.gov/pubmed/37275868
http://dx.doi.org/10.3389/fimmu.2023.1193175