Cargando…

The complement receptor C5aR2 regulates neutrophil activation and function contributing to neutrophil-driven epidermolysis bullosa acquisita

INTRODUCTION: The function of the second receptor for the complement cleavage product C5a, C5aR2, is poorly understood and often neglected in the immunological context. Using mice with a global deficiency of C5aR2, we have previously reported an important role of this receptor in the pathogenesis of...

Descripción completa

Detalles Bibliográficos
Autores principales: Seiler, Daniel L., Kähler, Katja H., Kleingarn, Marie, Sadik, Christian D., Bieber, Katja, Köhl, Jörg, Ludwig, Ralf J., Karsten, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235453/
https://www.ncbi.nlm.nih.gov/pubmed/37275893
http://dx.doi.org/10.3389/fimmu.2023.1197709