M-MDSC in vitro generation from mouse bone marrow with IL-3 reveals high expression and functional activity of arginase 1

Myeloid-derived suppressor cells (MDSC) represent major regulators of immune responses, which can control T cells via their inducible nitric oxide synthase (iNOS)- and arginase 1 (Arg1)-mediated effector functions. While GM-CSF is well documented to promote MDSC development, little is known about th...

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Detalles Bibliográficos
Autores principales: Aintablian, Arpa, Strozniak, Sandra, Heuer, Marion, Lutz, Manfred B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235456/
https://www.ncbi.nlm.nih.gov/pubmed/37275910
http://dx.doi.org/10.3389/fimmu.2023.1130600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235456/
https://www.ncbi.nlm.nih.gov/pubmed/37275910
http://dx.doi.org/10.3389/fimmu.2023.1130600

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