Cargando…
M-MDSC in vitro generation from mouse bone marrow with IL-3 reveals high expression and functional activity of arginase 1
Myeloid-derived suppressor cells (MDSC) represent major regulators of immune responses, which can control T cells via their inducible nitric oxide synthase (iNOS)- and arginase 1 (Arg1)-mediated effector functions. While GM-CSF is well documented to promote MDSC development, little is known about th...
Autores principales: | Aintablian, Arpa, Strozniak, Sandra, Heuer, Marion, Lutz, Manfred B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235456/ https://www.ncbi.nlm.nih.gov/pubmed/37275910 http://dx.doi.org/10.3389/fimmu.2023.1130600 |
Ejemplares similares
-
Circulating Myeloid Derived Suppressor Cells (MDSC) That Accumulate in Premalignancy Share Phenotypic and Functional Characteristics With MDSC in Cancer
por: Ma, Peiwen, et al.
Publicado: (2019) -
VLA-1 Binding to Collagen IV Controls Effector T Cell Suppression by Myeloid-Derived Suppressor Cells in the Splenic Red Pulp
por: Eckert, Ina N., et al.
Publicado: (2021) -
Arginase-1 Is Responsible for IL-13-Mediated Susceptibility to Trypanosoma cruzi Infection
por: Abad Dar, Mahin, et al.
Publicado: (2018) -
Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression
por: Tengesdal, Isak W., et al.
Publicado: (2021) -
Editorial: The role of epigenetic modification in MDSC differentiation and function
por: Tian, Xinyu, et al.
Publicado: (2023)