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E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism

OBJECTIVE: Gut microbiota and its metabolites have regulatory effects on PCOS related ovarian dysfunction and insulin resistance. Escherichia coli Nissle 1917 (EcN) is a genetically controlled probiotic with an excellent human safety record for improving gut microbiome metabolic disorders and immune...

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Detalles Bibliográficos
Autores principales: Luo, Man, Chen, Yuanyuan, Pan, Xiangyang, Chen, Hongmei, Fan, Lang, Wen, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235540/
https://www.ncbi.nlm.nih.gov/pubmed/37275915
http://dx.doi.org/10.3389/fimmu.2023.1137089