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E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism
OBJECTIVE: Gut microbiota and its metabolites have regulatory effects on PCOS related ovarian dysfunction and insulin resistance. Escherichia coli Nissle 1917 (EcN) is a genetically controlled probiotic with an excellent human safety record for improving gut microbiome metabolic disorders and immune...
Autores principales: | Luo, Man, Chen, Yuanyuan, Pan, Xiangyang, Chen, Hongmei, Fan, Lang, Wen, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235540/ https://www.ncbi.nlm.nih.gov/pubmed/37275915 http://dx.doi.org/10.3389/fimmu.2023.1137089 |
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