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Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam

OBJECTIVE: We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post‐traumatic seizures or neuromotor functional recovery (neuroscores), considering the effect of levetiracetam, which...

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Detalles Bibliográficos
Autores principales: Saletti, Patricia G., Mowrey, Wenzhu B., Liu, Wei, Li, Qianyun, McCullough, Jesse, Aniceto, Roxanne, Lin, I‐Hsuan, Eklund, Michael, Casillas‐Espinosa, Pablo M., Ali, Idrish, Santana‐Gomez, Cesar, Coles, Lisa, Shultz, Sandy R., Jones, Nigel, Staba, Richard, O'Brien, Terence J., Moshé, Solomon L., Agoston, Denes V., Galanopoulou, Aristea S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235584/
https://www.ncbi.nlm.nih.gov/pubmed/37026764
http://dx.doi.org/10.1002/epi4.12738