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Spatial distribution of tumor-infiltrating T cells indicated immune response status under chemoradiotherapy plus PD-1 blockade in esophageal cancer

BACKGROUND: The spatial distribution of tumor-infiltrating T cells and its dynamics during chemoradiotherapy combined with PD-1 blockade is little known in esophageal squamous cell carcinoma (ESCC). METHODS: We applied the multiplex immunofluorescence method to identify T cells (CD4(+), CD8(+) T cel...

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Detalles Bibliográficos
Autores principales: Yan, Cihui, Huang, Hui, Zheng, Zhunhao, Ma, Xiaoxue, Zhao, Gang, Zhang, Tian, Chen, Xi, Cao, Fuliang, Wei, Hui, Dong, Jie, Tang, Peng, Jiang, Hongjing, Wang, Meng, Wang, Ping, Pang, Qingsong, Zhang, Wencheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235618/
https://www.ncbi.nlm.nih.gov/pubmed/37275884
http://dx.doi.org/10.3389/fimmu.2023.1138054