Establishing plausibility of cardiovascular adverse effects of immunotherapies using Mendelian randomisation

Immune checkpoint inhibitors (ICIs) and Janus kinase inhibitors (JAKis) have raised concerns over serious unexpected cardiovascular adverse events. The widespread pleiotropy in genome-wide association studies offers an opportunity to identify cardiovascular risks from in-development drugs to help in...

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Detalles Bibliográficos
Autores principales: Le, Nhu Ngoc, Tran, Tran Quoc Bao, du Toit, Clea, Gill, Dipender, Padmanabhan, Sandosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235787/
https://www.ncbi.nlm.nih.gov/pubmed/37273876
http://dx.doi.org/10.3389/fcvm.2023.1116799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235787/
https://www.ncbi.nlm.nih.gov/pubmed/37273876
http://dx.doi.org/10.3389/fcvm.2023.1116799

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