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Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia

BACKGROUND: The aryl hydrocarbon receptor (AHR) is expressed in the intestine and liver, where it has pleiotropic functions and target genes. This study aims to explore the potential implication of AHR in cancer cachexia, an inflammatory and metabolic syndrome contributing to cancer death. Specifica...

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Detalles Bibliográficos
Autores principales: Dolly, Adeline, Pötgens, Sarah A., Thibaut, Morgane M., Neyrinck, Audrey M., de Castro, Gabriela S., Galbert, Chloé, Lefevre, Camille, Wyart, Elisabeth, Gomes, Silvio P., Gonçalves, Daniela C., Lanthier, Nicolas, Baldin, Pamela, Huot, Joshua R., Bonetto, Andrea, Seelaender, Marília, Delzenne, Nathalie M., Sokol, Harry, Bindels, Laure B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235873/
https://www.ncbi.nlm.nih.gov/pubmed/37127348
http://dx.doi.org/10.1002/jcsm.13246