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A Phase 1 study for safety and pharmacokinetics of BIO101 (20‐hydroxyecdysone) in healthy young and older adults

BACKGROUND: Sarcopenia is an age‐related skeletal muscle disorder characterized by loss of muscle mass and strength leading to mobility disability. 20‐Hydroxyecdysone (20E) is a polyhydroxylated plant steroid that demonstrates pharmacological effects in many disease animal models including ageing/sa...

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Detalles Bibliográficos
Autores principales: Dioh, Waly, Tourette, Cendrine, Del Signore, Susanna, Daudigny, Louiza, Dupont, Philippe, Balducci, Christine, Dilda, Pierre J., Lafont, René, Veillet, Stanislas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235879/
https://www.ncbi.nlm.nih.gov/pubmed/37057316
http://dx.doi.org/10.1002/jcsm.13195