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Evidence for inefficient contraction and abnormal mitochondrial activity in sarcopenia using magnetic resonance spectroscopy

BACKGROUND: Mitochondrial dysfunction has been implicated in sarcopenia. (31)P magnetic resonance spectroscopy (MRS) enables non‐invasive measurement of adenosine triphosphate (ATP) synthesis rates to probe mitochondrial function. Here, we assessed muscle energetics in older sarcopenic and non‐sarco...

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Detalles Bibliográficos
Autores principales: Stephenson, Mary C., Ho, Jamie X.M., Migliavacca, Eugenia, Kalimeri, Maria, Karnani, Neerja, Banerji, Subhasis, Totman, John J., Feige, Jerome N., Merchant, Reshma A., Tay, Stacey K.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235891/
https://www.ncbi.nlm.nih.gov/pubmed/37143433
http://dx.doi.org/10.1002/jcsm.13220