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Activation of skeletal muscle is controlled by a dual-filament mechano-sensing mechanism
Contraction of skeletal muscle is triggered by a transient rise in intracellular calcium concentration leading to a structural change in the actin-containing thin filaments that allows binding of myosin motors from the thick filaments. Most myosin motors are unavailable for actin binding in resting...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235942/ https://www.ncbi.nlm.nih.gov/pubmed/37216507 http://dx.doi.org/10.1073/pnas.2302837120 |