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Activation of skeletal muscle is controlled by a dual-filament mechano-sensing mechanism

Contraction of skeletal muscle is triggered by a transient rise in intracellular calcium concentration leading to a structural change in the actin-containing thin filaments that allows binding of myosin motors from the thick filaments. Most myosin motors are unavailable for actin binding in resting...

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Detalles Bibliográficos
Autores principales: Brunello, Elisabetta, Marcucci, Lorenzo, Irving, Malcolm, Fusi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235942/
https://www.ncbi.nlm.nih.gov/pubmed/37216507
http://dx.doi.org/10.1073/pnas.2302837120

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