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Redox states in the endoplasmic reticulum directly regulate the activity of calcium channel, inositol 1,4,5-trisphosphate receptors
Inositol 1,4,5-trisphosphate receptors (IP3Rs) are one of the two types of tetrameric ion channels that release calcium ion (Ca(2+)) from the endoplasmic reticulum (ER) into the cytosol. Ca(2+) released via IP3Rs is a fundamental second messenger for numerous cell functions. Disturbances in the intr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235943/ https://www.ncbi.nlm.nih.gov/pubmed/37216546 http://dx.doi.org/10.1073/pnas.2216857120 |