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The autism-associated loss of δ-catenin functions disrupts social behavior

δ-catenin is expressed in excitatory synapses and functions as an anchor for the glutamatergic AMPA receptor (AMPAR) GluA2 subunit in the postsynaptic density. The glycine 34 to serine (G34S) mutation in the δ-catenin gene has been found in autism spectrum disorder (ASD) patients and results in loss...

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Detalles Bibliográficos
Autores principales: Mendez-Vazquez, Hadassah, Roach, Regan L., Nip, Kaila, Chanda, Soham, Sathler, Matheus F., Garver, Tyler, Danzman, Rosaline A., Moseley, Madeleine C., Roberts, Jessica P., Koch, Olivia N., Steger, Ava A., Lee, Rahmi, Arikkath, Jyothi, Kim, Seonil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235948/
https://www.ncbi.nlm.nih.gov/pubmed/37216537
http://dx.doi.org/10.1073/pnas.2300773120