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Mechanosensitive stem cell fate choice is instructed by dynamic fluctuations in activation of Rho GTPases

During the intricate process by which cells give rise to tissues, embryonic and adult stem cells are exposed to diverse mechanical signals from the extracellular matrix (ECM) that influence their fate. Cells can sense these cues in part through dynamic generation of protrusions, modulated and contro...

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Detalles Bibliográficos
Autores principales: Sampayo, Rocío G., Sakamoto, Mason, Wang, Madeline, Kumar, Sanjay, Schaffer, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235963/
https://www.ncbi.nlm.nih.gov/pubmed/37216516
http://dx.doi.org/10.1073/pnas.2219854120