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Mechanosensitive stem cell fate choice is instructed by dynamic fluctuations in activation of Rho GTPases
During the intricate process by which cells give rise to tissues, embryonic and adult stem cells are exposed to diverse mechanical signals from the extracellular matrix (ECM) that influence their fate. Cells can sense these cues in part through dynamic generation of protrusions, modulated and contro...
Autores principales: | Sampayo, Rocío G., Sakamoto, Mason, Wang, Madeline, Kumar, Sanjay, Schaffer, David V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235963/ https://www.ncbi.nlm.nih.gov/pubmed/37216516 http://dx.doi.org/10.1073/pnas.2219854120 |
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