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Mechanoepigenetic regulation of extracellular matrix homeostasis via Yap and Taz

Cells integrate mechanical cues to direct fate specification to maintain tissue function and homeostasis. While disruption of these cues is known to lead to aberrant cell behavior and chronic diseases, such as tendinopathies, the underlying mechanisms by which mechanical signals maintain cell functi...

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Detalles Bibliográficos
Autores principales: Jones, Dakota L., Hallström, Grey F., Jiang, Xi, Locke, Ryan C., Evans, Mary Kate, Bonnevie, Edward D., Srikumar, Anjana, Leahy, Thomas P., Nijsure, Madhura P., Boerckel, Joel D., Mauck, Robert L., Dyment, Nathaniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235980/
https://www.ncbi.nlm.nih.gov/pubmed/37216538
http://dx.doi.org/10.1073/pnas.2211947120