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Mechanoepigenetic regulation of extracellular matrix homeostasis via Yap and Taz
Cells integrate mechanical cues to direct fate specification to maintain tissue function and homeostasis. While disruption of these cues is known to lead to aberrant cell behavior and chronic diseases, such as tendinopathies, the underlying mechanisms by which mechanical signals maintain cell functi...
Autores principales: | Jones, Dakota L., Hallström, Grey F., Jiang, Xi, Locke, Ryan C., Evans, Mary Kate, Bonnevie, Edward D., Srikumar, Anjana, Leahy, Thomas P., Nijsure, Madhura P., Boerckel, Joel D., Mauck, Robert L., Dyment, Nathaniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235980/ https://www.ncbi.nlm.nih.gov/pubmed/37216538 http://dx.doi.org/10.1073/pnas.2211947120 |
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