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Primary cilia TRP channel regulates hippocampal excitability

Polycystins (PKD2, PKD2L1, and PKD2L2) are members of the transient receptor potential family, which form ciliary ion channels. Most notably, PKD2 dysregulation in the kidney nephron cilia is associated with polycystic kidney disease, but the function of PKD2L1 in neurons is undefined. In this repor...

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Detalles Bibliográficos
Autores principales: Vien, Thuy N., Ta, My C., Kimura, Louise F., Onay, Tuncer, DeCaen, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235993/
https://www.ncbi.nlm.nih.gov/pubmed/37216541
http://dx.doi.org/10.1073/pnas.2219686120