Cargando…
Osteolectin increases bone elongation and body length by promoting growth plate chondrocyte proliferation
Osteolectin is a recently identified osteogenic growth factor that binds to Integrin α11 (encoded by Itga11), promoting Wnt pathway activation and osteogenic differentiation by bone marrow stromal cells. While Osteolectin and Itga11 are not required for the formation of the skeleton during fetal dev...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235998/ https://www.ncbi.nlm.nih.gov/pubmed/37216542 http://dx.doi.org/10.1073/pnas.2220159120 |