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Osteolectin increases bone elongation and body length by promoting growth plate chondrocyte proliferation

Osteolectin is a recently identified osteogenic growth factor that binds to Integrin α11 (encoded by Itga11), promoting Wnt pathway activation and osteogenic differentiation by bone marrow stromal cells. While Osteolectin and Itga11 are not required for the formation of the skeleton during fetal dev...

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Detalles Bibliográficos
Autores principales:	Zhang, Jingzhu, Du, Liming, Davis, Bethany, Gu, Zhimin, Lyu, Junhua, Zhao, Zhiyu, Xu, Jian, Morrison, Sean J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10235998/ https://www.ncbi.nlm.nih.gov/pubmed/37216542 http://dx.doi.org/10.1073/pnas.2220159120

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