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Induction by rapamycin and proliferation‑promoting activity of Hspb1 in a Tsc2‑deficient cell line

Tuberous sclerosis complex (TSC) is an intractable inherited disease caused by a germline mutation in either the TSC complex subunit 1 (TSC1) or TSC2 tumor suppressor genes. Recent progress in the treatment of TSC with rapamycin has provided benefits to patients with TSC. However, the complete elimi...

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Detalles Bibliográficos
Autores principales: Kitano, Takayuki, Nishikawa, Keiko, Takagaki, Tetsuya, Sugitani, Yoshinobu, Hino, Okio, Kobayashi, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236050/
https://www.ncbi.nlm.nih.gov/pubmed/37273756
http://dx.doi.org/10.3892/etm.2023.12014