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Influence of Adipose Tissue Distribution, Sarcopenia, and Nutritional Status on Clinical Outcomes After CD19 CAR T-cell Therapy

Although CD19-directed chimeric antigen receptor T-cell therapy (CD19.CAR-T) has proven clinical efficacy for multiple refractory B-cell malignancies, over 50% of patients ultimately relapse. Recent evidence has underlined the critical role of the host in determining treatment responses. In this ret...

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Detalles Bibliográficos
Autores principales: Rejeski, Kai, Cordas dos Santos, David M., Parker, Nathan H., Bücklein, Veit L., Winkelmann, Michael, Jhaveri, Khushali S., Liu, Lian, Trinkner, Paul, Günther, Sophie, Karschnia, Philipp, Blumenberg, Viktoria, Schmidt, Christian, Kunz, Wolfgang G., von Bergwelt-Baildon, Michael, Jain, Michael D., Theurich, Sebastian, Subklewe, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236147/
https://www.ncbi.nlm.nih.gov/pubmed/37040425
http://dx.doi.org/10.1158/2326-6066.CIR-22-0487