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Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia

Intestinal metaplasia in the esophagus (Barrett's esophagus IM, or BE-IM) and stomach (GIM) are considered precursors for esophageal and gastric adenocarcinoma, respectively. We hypothesize that BE-IM and GIM follow parallel developmental trajectories in response to differing inflammatory insul...

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Detalles Bibliográficos
Autores principales: Nowicki-Osuch, Karol, Zhuang, Lizhe, Cheung, Tik Shing, Black, Emily L., Masqué-Soler, Neus, Devonshire, Ginny, Redmond, Aisling M., Freeman, Adam, di Pietro, Massimilliano, Pilonis, Nastazja, Januszewicz, Wladyslaw, O'Donovan, Maria, Tavaré, Simon, Shields, Jacqueline D., Fitzgerald, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236154/
https://www.ncbi.nlm.nih.gov/pubmed/36929873
http://dx.doi.org/10.1158/2159-8290.CD-22-0824