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Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions

The adult healthy human pancreas has been poorly studied given the lack of indication to obtain tissue from the pancreas in the absence of disease and rapid postmortem degradation. We obtained pancreata from brain dead donors, thus avoiding any warm ischemia time. The 30 donors were diverse in age a...

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Detalles Bibliográficos
Autores principales: Carpenter, Eileen S., Elhossiny, Ahmed M., Kadiyala, Padma, Li, Jay, McGue, Jake, Griffith, Brian D., Zhang, Yaqing, Edwards, Jacob, Nelson, Sarah, Lima, Fatima, Donahue, Katelyn L., Du, Wenting, Bischoff, Allison C., Alomari, Danyah, Watkoske, Hannah R., Mattea, Michael, The, Stephanie, Espinoza, Carlos E., Barrett, Meredith, Sonnenday, Christopher J., Olden, Nicholas, Chen, Chin-Tung, Peterson, Nicole, Gunchick, Valerie, Sahai, Vaibhav, Rao, Arvind, Bednar, Filip, Shi, Jiaqi, Frankel, Timothy L., Pasca di Magliano, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236159/
https://www.ncbi.nlm.nih.gov/pubmed/37021392
http://dx.doi.org/10.1158/2159-8290.CD-23-0013