Soluble NKG2D ligands impair CD8(+) T cell antitumor function dependent of NKG2D downregulation in neuroblastoma

T cell-based immunotherapy has achieved remarkable beneficial clinical outcomes. Tumor-derived NKG2D ligands (NKG2DL) allow tumors to escape immunologic surveillance. However, the mechanism underlying NKG2DL-mediated immune escape in neuroblastoma (NB) remains incompletely understood. In the present...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yi, Luo, Feifei, Dong, Kuiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236264/
https://www.ncbi.nlm.nih.gov/pubmed/37274476
http://dx.doi.org/10.3892/ol.2023.13883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236264/
https://www.ncbi.nlm.nih.gov/pubmed/37274476
http://dx.doi.org/10.3892/ol.2023.13883

Ejemplares similares