Outlook of PINK1/Parkin signaling in molecular etiology of Parkinson’s disease, with insights into Pink1 knockout models

Parkinson’s disease (PD) relates to defective mitochondrial quality control in the dopaminergic motor network. Genetic studies have revealed that PINK1 and Parkin mutations are indicative of a heightened propensity to PD onset, pinpointing mitophagy and inflammation as the culprit pathways involved...

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Detalles Bibliográficos
Autores principales: Wang, Zhangting, Chan, See-Wing, Zhao, Hui, Miu, Kai-Kei, Chan, Wai-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236303/
https://www.ncbi.nlm.nih.gov/pubmed/37161651
http://dx.doi.org/10.24272/j.issn.2095-8137.2022.406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236303/
https://www.ncbi.nlm.nih.gov/pubmed/37161651
http://dx.doi.org/10.24272/j.issn.2095-8137.2022.406

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