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Depletion of microglia with PLX3397 attenuates MK-801-induced hyperactivity associated with regulating inflammation-related genes in the brain

Acute administration of MK-801 (dizocilpine), an N-methyl-D-aspartate receptor (NMDAR) antagonist, can establish animal models of psychiatric disorders. However, the roles of microglia and inflammation-related genes in these animal models of psychiatric disorders remain unknown. Here, we found rapid...

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Detalles Bibliográficos
Autores principales: Ni, Rong-Jun, Wang, Yi-Yan, Gao, Tian-Hao, Wang, Qi-Run, Wei, Jin-Xue, Zhao, Lian-Sheng, Ma, Yang-Rui, Ma, Xiao-Hong, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236309/
https://www.ncbi.nlm.nih.gov/pubmed/37147908
http://dx.doi.org/10.24272/j.issn.2095-8137.2022.389