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Cell type deconvolution of methylated cell-free DNA at the resolution of individual reads

Cell-free DNA (cfDNA) are DNA fragments originating from dying cells that are detectable in bodily fluids, such as the plasma. Accelerated cell death, for example caused by disease, induces an elevated concentration of cfDNA. As a result, determining the cell type origins of cfDNA molecules can prov...

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Detalles Bibliográficos
Autores principales: Keukeleire, Pia, Makrodimitris, Stavros, Reinders, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236360/
https://www.ncbi.nlm.nih.gov/pubmed/37274121
http://dx.doi.org/10.1093/nargab/lqad048