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Cell type deconvolution of methylated cell-free DNA at the resolution of individual reads
Cell-free DNA (cfDNA) are DNA fragments originating from dying cells that are detectable in bodily fluids, such as the plasma. Accelerated cell death, for example caused by disease, induces an elevated concentration of cfDNA. As a result, determining the cell type origins of cfDNA molecules can prov...
Autores principales: | Keukeleire, Pia, Makrodimitris, Stavros, Reinders, Marcel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236360/ https://www.ncbi.nlm.nih.gov/pubmed/37274121 http://dx.doi.org/10.1093/nargab/lqad048 |
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