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3plex enables deep computational investigation of triplex forming lncRNAs

Long non-coding RNAs (lncRNAs) regulate gene expression through different molecular mechanisms, including DNA binding via the formation of RNA:DNA:DNA triple helices (TPXs). Despite the increasing amount of experimental evidence, TPXs investigation remains challenging. Here we present 3plex, a softw...

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Detalles Bibliográficos
Autores principales: Cicconetti, Chiara, Lauria, Andrea, Proserpio, Valentina, Masera, Marco, Tamburrini, Annalaura, Maldotti, Mara, Oliviero, Salvatore, Molineris, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10236371/
https://www.ncbi.nlm.nih.gov/pubmed/37273849
http://dx.doi.org/10.1016/j.csbj.2023.05.016